Exception calling ".ctor" with "1" argument(s): "Object reference not set to an instance of an object."
When running a command in the SharePoint 2010 Management Shell against User Profiles you receive the following error:
New-Object : Exception calling ".ctor" with "1" argument(s): "Object reference not set to an instance of an object."
Solution:
Ensure the user executing the command has Full Control permission over the User Profile Service Application

